Arsenal face a second consecutive London Derby when they play West Ham on Saturday.
The Gunners are set to come up against Jack Wilshere for the first time since he left Arsenal for the Hammers last month, with the Englishman revealing that he won't celebrate if he scores against his old club.
Unai Emery will pit his wits against Manuel Pellegrini once again after 10 previous meetings in La Liga, where the Spaniard won three, drew three and lost four.
Left-back Sead Kolasinac is out for eight to ten weeks with a knee injury while Ainsley Maitland-Niles has suffered a fracture in his left leg and will be out for six to eight weeks.
Long-term absentee Laurent Koscielny is aiming to return to training in November, as will Carl Jenkinson who has a significant sprain to his right ankle.
Arsenal have no suspensions for this game.
Possible Arsenal starting line-up
Emery could hand Lucas Torreira his first full Premier League start in defensive midfield while Nacho Monreal or Stephan Lichtsteiner will start at left-back.
Alex Iwobi is expected to continue on the left hand side while Mesut Ozil and Henrikh Mkhitaryan will almost certainly support Pierre-Emerick Aubameyang up top.
West Ham team news
Mark Noble faces a fitness test ahead of Saturday's game while Wilshere could also start against his former club.
Long term absentees Andy Carroll, Manuel Lanzini and Winston Reid are the only other players definitely unavailable for selection.
TV coverage & kick-off time
Kick-off is 3pm BST (10am ET) on Saturday August 25, and the game will not be shown on TV in the United Kingdom. It will be shown on NBC in the United States, and on various channels around the world.
Best Opta match facts
Arsenal have lost one of their last 22 matches against West Ham in all competitions (W17 D4), losing 2-0 on the opening day of the 2015-16 season.
Arsenal haven’t lost a Premier League London derby match at the Emirates Stadium since January 2016 (0-1 vs Chelsea), winning six and drawing three of their derby games at the Stadium since then.
Unai Emery faced Manuel Pellegrini on 10 occasions in La Liga, winning three, drawing three and losing four – Emery won his two most recent home league matches against the Chilean, doing so in January 2011 (Valencia 4-3 Malaga) and December 2011 (Valencia 2-0 Malaga).
Arsenal’s Matteo Guendouzi has made 17 tackles & interceptions (combined) in the opening two matchdays of this Premier League season; four more than any other player.