Goals from Keita Balde and Krepin Diatta condemned Emmanuel Amuneke’s men to a 2-0 loss at the 30 June Stadium on Sunday.
The Taifa Stars are making a return to the African showpiece after 39 years, having last featured in the tournament in 1980.
Notwithstanding the defeat against the best-ranked African side, Magufuli has charged Tanzanians to continue backing the team who helped them end their long wait of qualifying for the Afcon tournament.
“Let’s give the Taifa Stars morale support. We need to encourage the players. Despite losing to the number one team on the African continent,” he said, per the Citizens.
“They deserve commendations as the players are the ones who made the country qualify for the Africa Cup of Nations after a period of 39 years.”
The Taifa Stars will hope for a positive result when they take on their East African neighbours, Kenya in their second Group C match in the tournament on Thursday.
Tanzania are aiming to progress past the group stage of the continental competition for the first time in their history.