The fixtures for the 2011-12 season have been announced, and it appears that Liverpool new boy Jordan Henderson is set to face his former club Sunderland on the opening day of the season.
Elsewhere, Manchester United begin their title defence with a trip to play West Brom on August 13, while Arsenal travel to take on Newcastle United at St James' Park. Tottenham host Everton, while Manchester City host newcomers Swansea City at Eastlands.
The Gunners are presented with a clash against Liverpool at home in the second week of the season before taking on United at Old Trafford.
Tottenham also have a difficult start to the season, as their campaign's first three fixtures are Everton at home, United away and Manchester City at home.
The Red Devils have an important set of fixtures in October, when they first lock horns with fierce rivals Liverpool on October 15, with the Manchester derby up next on October 22, and a trip to Goodison Park on October 29.
The first north London derby is scheduled to take place on October 1 at White Hart Lane, with the first Merseyside derby also taking place the same weekend. As for the battle for supremacy in Manchester, the first meeting between the two sides in the league is set to take place on October 22 at Old Trafford.
Boxing Day sees a London derby taking place between Chelsea and Fulham, while new arrivals Swansea City and Queens Park Rangers lock horns at the Liberty Stadium.
Potential title deciders in the form of a clash between Chelsea and Liverpool takes place at Stamford Bridge in the penultimate weekend of the season, while the Manchester derby takes place at Eastlands a week before.
Arsenal end their campaign on May 13 with a trip to West Brom, while Chelsea finish against Blackburn Rovers at home. Manchester City take on QPR while their arch-rivals United end their title defence against Sunderland away, with Liverpool finishing away to Swansea.
As for Spurs, they host Fulham in an all-London clash on the final day of the season.
Opening day fixtures: Saturday, August 13
Blackburn Rovers v Wolves
Fulham v Aston Villa
Liverpool v Sunderland
Manchester City v Swansea City
Newcastle United v Arsenal
QPR v Bolton
Stoke City v Chelsea
Tottenham Hotspur v Everton
West Brom v Manchester United
Wigan Athletic v Norwich City