Universidad Catolica continued their positive start to the Clausura with a resounding victory over Union La Calera to stay at the top with three matches played. Former Penarol midfielder Matias Mier fired the Cruzado into the lead with two first-half strikes, before Cesar Carignano and Felipe Gutierrez scored to seal a 4-0 drubbing at home.
Elsewhere Colo Colo collapsed in the second-half to fall to a painful 3-0 victory away to Universidad de Concepcion. Universidad de Chile meanwhile made it two wins out of two in the new season with a 3-1 reverse of Cobreloa. Argentine Gustavo Lorenzetti was the hero with two goals to see off the opposition in Sunday's match.
An incredible five-goal haul from Hernan Barcos was the key for Liga de Quito as they stormed to a 6-0 victory over Manta FC in the fifth round of the Segunda Fase in Ecuador. The away side had no answer to the Argentine striker as he netted a quintet of goals in less than 30 minutes, earning Liga their third win of the season.
Liga's city rivals Deportivo Quito continue to brush aside all-comers, recording a fifth straight win over Espoli in a routine 2-0 victory. The Guayaquil derby meanwhile finished in a stalemate, as Barcelona hit a last-minute equaliser to cancel out Luis Caicedo's opener and rescue a 1-1 draw against Emelec.
The highlight of the Paraguayan weekend is scheduled for Monday evening, when Olimpia take on Libertad in what promises to be a fiercely-contested Asuncion derby. Olimpia have recorded two wins out of two so far, and will go top if they can take down the Repolleros away from home tonight.
Apertura champions Nacional currently occupy the Clausura summit with seven points and they cemented their place at the top with a narrow 1-0 victory away to Sol de America. Cerro Porteno meanwhile dropped their first points of the year, going down to a surprise 1-0 defeat at home to Independiente CG.
Marcelo Gallardo could not celebrate a debut victory as coach of Nacional, after the 2010-11 champions played out an entertaining 3-3 draw away to River Plate. The Bolso recovered from a two goal deficit to go ahead 3-2 late in the second half, Alvaro Recoba finding the net in his first match since moving from Danubio. Maureen Franco ruined Nacional's party, however, scoring in the 87th minute to rescue a point.
Copa Libertadores finalists Penarol saw their game with Bella Vista postponed, but the rest of the Uruguayan league kicked into action over the weekend. Defensor Sporting overcame Rampla Juniors 2-0 to record three points, while Cerro, Danubio and Fenix were other winners in the first weekend of the Apertura.
Venezuela also saw the resumption of league hostilities, kicking off the first weekend of the 2011 Apertura. Current champions Deportivo Tachira were held to a 1-1 draw by Deportivo Lara, while Zamora FC impressed in downing Tucanes de Amazonas 3-1 away from home to sit at the top of the table after one game.