El Tri open their tournament on Friday when they meet Bolivia in Viña del Mar, and little has been expected of them in some quarters after Herrera left out the likes of Guillermo Ochoa, Andres Guardado, Giovani dos Santos, Javier 'Chicharito' Hernandez and Carlos Vela with a view to sending a refreshed group to the Concacaf Gold Cup in July.
But Herrera says he has every belief that Mexico will challenge for the Copa America crown despite the vast amount of experience they have left at home.
"[We have brought] some stars, the best goalkeeper in Mexico at the moment in Jose Corona. There are Liguilla players, World Cup players, Rafa Marquez who has played in four World Cups," the coach told a pre-match press conference.
"Mexico is the only national team in the world that can play in two different confederations, which is great. We can play Copa America, and also the Gold Cup, which is our confederation.
"This is why we need two teams in order to play these competitions, but that doesn't mean that this is the B one.
"People here want to make it to the final and win it. That's our aim for the Copa America."
Chile and Ecuador also stand in Mexico's way as they hope to emerge from Group A, but Herrera revealed that his team have prepared as well as possible for the task ahead.
"Our training sessions have been really good. It was very demanding with such a high level of intensity, that I now have some doubts over who to select in my team, which is great," he explained.
"It means I have every player available, and looking forward to playing. Like I said before, the 11 players who represent us, those 11 will try to go out there and make history. Spirits are high in the squad, and we want to win this opening match.
"It's beyond a doubt that my players are nervous, but it’s the kind of anxiety you have in a big tournament, and can't wait to play.
"There's obviously pressure. This is Mexico, and there's always expectation. There are many great teams in this competition, and we have to be able to win three games, in order to play a fourth, fifth and hopefully a sixth."
Mexico reached the round of 16 at the 2014 World Cup, only to lose 2-1 to Netherlands courtesy of a pair of late goals.