Atletico Madrid boss Quique Sanchez Flores says now is the time to break their 11-year derby drought against city rivals Real Madrid.
Both sides meet on Saturday at the Vicente Calderon, and the last time Los Colchoneros triumphed in the clash was October 1999.
With hopes of qualifying for Europe still intact, the coach wants a big performance, saying: "Of all the games we have played against Real Madrid, this is the one we confront with most happiness.
"We are doing well, and the work rate is good to win. We are convinced we can win and break the cycle. We are all well, and everyone available will be in the squad as we want to live this together tomorrow as it is important for everyone and I want them all involved.
"We want to end the cycle, and if we win tomorrow them everyone will remember this season as being the one in which we beat Real Madrid."
Check out the video below to see EA Sports' FIFA 2011 simulation of the match: