Marca reported earlier on Wednesday that Barcelona are planning to sell the Spain international to the highest bidder from the English Premier League, with Chelsea and Liverpool allegedly interested in Villa's services, but Guardiola has stressed that there's no truth in the rumour.
"They are lying," reacted the Barcelona boss to the report.
The 30-year-old striker joined Barcelona from Valencia for a fee in the region of €40 million in the summer of 2010 and immediately became an important first-team member in his debut season with the Catalans.
However, Villa has been struggling to secure a regular berth in the starting XI in the 2011-12 campaign and has frequently been used only as a substitute due to the competition for place following the arrivals of Alexis Sanchez and Cesc Fabregas.
Villa's current contract with Barcelona runs until the summer of 2014.
Starting last month and continuing every Friday through to January, Goal.com will publish extracts from Graham Hunter's highly-anticipated book, Barca: The Making of the Greatest Team in the World. The most recent extract detailed how Jose Mourinho's Real Madrid have closed the gap on Barca following a period of Catalan dominance.