Many critics have suggested that the cup competition could make or break the Nerazzurri's season as they tumble down the Serie A table, with a 2-0 defeat at Cagliari the latest in their long line of dropped points in 2013.
However, the 37-year-old was adamant that the decision as to whether he remains in charge at San Siro will be made at the end of the season based on their overall performance and this week's Coppa Italia clash.
"There's no point judging my work and the team at this stage - everyone can have their say later,” Stramaccioni insisted on Tuesday to reporters.
"Then we'll see where we are, but I don't think my future will be decided by tomorrow, but by what I've done over the course of a year.
"Although tomorrow's match is very important, I don't think it will make or break my future or other issues. The president [Massimo Moratti] will give his verdict at the end, not based on Inter versus Roma, but on the season as a whole.
"It’s too soon to start making judgements, or to talk about the future, on the eve of such an important match."
Inter welcome the Giallorossi to San Siro hoping to overturn a 2-1 deficit from the first leg and the coach refused to use injuries as an excuse heading into what he believes will be a difficult - but winnable - battle.
"Roma are an excellent side and we've not even beaten them when we've been at full strength," Stramaccioni continued. "It will be a very tough match, but we are up for it and want to upset the odds.
"We've had this injury crisis for a while now, we've never used it as an excuse and we won't start now. In fact, I'm sure we'll have added motivation and strength to get a result which some people think is beyond us."
Stramaccioni refused to divulge transfer targets but admitted that Moratti is hard at work looking for viable players to bolster the squad for next season during the summer window.
"The president has clear ideas on this, the club are already at work, based on what went on this season, whilst keeping in mind that, despite negative results, some players have stood out," he added.
“Either way, the club has already finalised a number of deals and I was consulted on them, but I don't know if this means anything. I'll bring the season to a close in the best way possible and then the president will decide whether to stick with me or go for another coach."