Coach Jimmy Cobblah's 18-man travelling party includes Saliw Babawo of Belarusian side Dinamo Brest, Belgium-based goalkeeper Abdul Manaf Nurudeen, Abdul Halik Hudu of Hammarby of Sweden and Ibrahim Tanko of Serbian club Red Star Belgrade.
The team also includes six players from the side that played at last year's Fifa Under-17 World Cup in India.
The players include Kotoko goalkeeper Ibrahim Danlad, the Right to Dream trio of Mohammed Kudus, Gideon Mensah and Sadiq Ibrahim, Wafa's Richard Danso and Rising Star winger Sulley Ibrahim.
Friday's fixture is a second round first leg tie.
Ghana drew a bye for the first phase while Algeria beat Tunisia 5-2 on aggregate to progress.
The winners over two legs set up a date with Gambia/Benin in the third and final round slated for July.
Seven teams are expected to join hosts Niger for the final championship.
The Black Satellite are hoping to make a return to the U-20 Afcon after failing to qualify for the last edition in 2017.
Ibrahim Danlad (Asante Kotoko), Emmanuel Kumah (Tudu Mighty Jets), Umar Basit Abdul Raman (New Edubiase United), Mohammed Kudus (Right To Dream), Gideon Mensah (Right To Dream), Sadiq Ibraham (Right To Dream), Maxwell Arthur (Dreams FC), Adjetey Daniel Adrain (Amidaus Professionals), Saliw Babawo (FC Dinamo Brest, Belarus), Abdul Manaf Nurudeen (Kas Eupen, Belgium), Arthur Jude Ekow (Liberty Professionals), Richard Danso (Wafa), Isshaku Konda (Wa All Stars), Sulley Ibrahim (Rising Star), Prosper Dayegbe Ahiabu (Wafa), Abdul Halik Hudu (Hammarby IF, Sweden), Hamidu Abdul Fatawu (Vision FC), Ibrahim Tanko (Red Star Belgrade, Serbia)