After signing for English side Tottenham Hotspur in 2007, the Ghanaian was forced out on a half-season loan at Dortmund in the 2008-09 season due to limited opportunities with the Lilywhites.
He made 10 league appearances in all – involving four starts – as the Black and Yellows finished sixth on the league table.
“Definitely - I always enjoy playing against my former clubs,” Boateng told his club’s official website when asked whether Saturday’s fixture is of special interest.
“I had a very good time at Dortmund. I’ll come face to face with a lot of old friends, so it’s going to be very emotional.
“I look forward to every game though, particularly at home. Everyone who has set foot in our stadium knows about the incredible atmosphere here.
“The Frankfurt fans are exceptional. It’s going to be a great game on Saturday and I obviously hope we can get a positive result for our fans.”
Dortmund are not a happy side at the moment as Peter Bosz’s outfit have drawn one and lost one of their last two games in all competitions.
However, Boateng is not pushing his team’s chances too high.
“Obviously, Dortmund didn’t reach their full potential in their last two games, but we know exactly what we’re up against,” said, the 30-year-old.
“Overall I regard Dortmund as one of the strongest teams in Europe.
“They play the most attractive brand of football imaginable.
“I’m convinced we’ll be able to create chances against them, though.”
Boateng joined Frankfurt during the summer transfer window. The Eagles currently sit seventh on the Bundesliga table.