Having failed to secure victory in their last five games, Eusebio Di Francesco’s men will be eager to bounce back to winning ways.
They boast of an advantage on head to head having won 20 of their last 42 meetings with their hosts and lost only 11.
However, they face an uphill task in leaving Stadio Luigi Ferraris with maximum points as they have only triumphed in one of their last eight visits there. Punters who are bold can back them to come out on top at the price of (1.90) with Bet365.
A draw at the end of 90 minutes is a possibility at odds of (3.60).
Sampdoria will be hoping to continue their impressive home record lately after winning against SPAL before securing another victory over Fiorentina last time out.
However, having lost three of their previous four meetings with Giallorossi, they have been tagged as slight underdogs for this clash at the price of (3.80).
Roma earned a point against Inter Milan at Stadio Giuseppe Meazza in their last engagement and odds of (1.28) has been quoted for them to avoid defeat in this tie.
Six of their previous meetings produced 22 goals and the betting firm is tipping (1.65) for over 2.5 goals to surface.
*Odds correct at the time of writing. Please gamble responsibly.