Clint Dempsey is just one goal away from matching Landon Donovan's all-time USA scoring record and will get a chance to go at from the start in Saturday night's friendly against Venezuela.
Joining the veteran in the attack are Borussia Dortmund youngster Christian Pulisic and Bobby Wood, who is making his first appearance of 2017.
Fabian Johnson and DeAndre Yedlin are both also making their first appearances of the year as Bruce Arena calls on a strong side to kick off a busy summer, with Geoff Cameron and John Brooks manning the back line in front of Tim Howard.
Darlington Nagbe, Jorge Villafana and Michael Bradley round out the side, with the Toronto midfielder wearing the captain's armband.
USA starting XI vs. Venezuela: 1-Tim Howard, 2-DeAndre Yedlin, 4-Michael Bradley (capt.), 6-John Brooks, 8-Clint Dempsey, 9-Bobby Wood, 10-Christian Pulisic, 15-Darlington Nagbe, 17-Jorge Villafaña, 20-Geoff Cameron, 23-Fabian Johnson
Substitutes: 22-Nick Rimando, 3-Omar Gonzalez, 11-Alejandro Bedoya, 13-Dax McCarty, 14-Tim Ream, 16-Kellyn Acosta, 18-Jordan Morris, 19-Graham Zusi, 21-Matt Hedges