The player nicknamed 'The Ox' was deployed in central midfield as Steve Bould stepped in for the suspended Arsene Wenger, and had an excellent game for the Gunners.
Arsenal fans showed their appreciation on Twitter, with some comparing the 23-year-old England international to midfield legends Andrea Pirlo and Xavi.
The Ox is playing like a prime Andrea Pirlo tonight.— Ö (@OliPriceBates) January 28, 2017
No idea why some Arsenal fans don't rate the Ox.— GeoffArsenal (@GeoffArsenal) January 28, 2017
Always thought it was his best position. Trouble is he won't get in the side there— Lee Dixon (@LeeDixon2) January 28, 2017
Big shoutout to Ox. Played as CM after a long time, not his actual position and had Maitland-Niles besides him. Both did a great job.— Sir Jenkinson (@theEpicGooner) January 28, 2017
Bould has transformed Ox into a prime Pirlo in one game..Tears in my eyes— Xhakahari (@Cechque) January 28, 2017
Ox-Coq midfield pairing whilst Xhaka is out looks a possibility.— The Arsenal (@DareToWenger) January 28, 2017
I'd like to thank Perrie Edwards for this Ox performance this afternoon— The Arsenist (@AngryGooner21) January 28, 2017
Alex Oxlade-Chamberlain has been absolutely brilliant today. Unplayable. So good to see him do well.— #10 (@WengerTactic) January 28, 2017
3 of Oxlade-Chamberlain's best performances have come in the middle. Milan, Bayern & now Southampton. He could be some player in there. #afc— Pablo (@AFCAMDEN) January 28, 2017
Oxlade-Chamberlain looked phenomenal in the middle today, great passing & drive, really put down a marker, hopefully he keeps it up #AFC— Patrick Timmons (@PatrickTimmons1) January 28, 2017
Maitland-Niles and Oxlade Chamberlain are the new Vieira and Petit.— Pablo (@AFCAMDEN) January 28, 2017
Xavi looking up at Ox's performance with tears in his eyes.— Invincible (@UnrealMonrealFC) January 28, 2017
Oxlade-Chamberlain has made just eight Premier League starts this season, but his cup performance will give Wenger and Bould plenty to consider ahead of Tuesday's clash with Watford.