Arsenal were due to face Vorskla in the city of Poltava on Thursday, with the Gunners top of Group E on 10 points.
"UEFA's Emergency Panel has today taken the decision to relocate Vorskla's Europa League group stage match against Arsenal from the city of Poltava, following the introduction of martial law into certain regions in Ukraine," a statement from UEFA said.
"The match will now take place at the Olimpiyskiy Stadium in Kyiv on Thursday 29 November at 18.55 CET. UEFA will continue to monitor and assess the security situation in Ukraine in the coming days before making any decision on potentially relocating other matches."
Arsenal are already assured of a place in the knockout rounds and will guarantee first place in Group E with a win, while Vorskla need a victory to keep their qualification hopes intact.
The Gunners will be looking to stretch a 17-game unbeaten run in midweek.
Unai Emery's side have been making impressive progress, but Sokratis Papastathopoulos has warned that there is even more to come.
He said: "We are around 70 to 80 per cent [of our potential].
"Of course we need to improve, of course we would like to put Arsenal in the top teams in the Premier League. We try every day for this.
"We need to improve sometimes to not lose the ball, or when we have the ball to finish the action and score.
"That is the difference, we need to improve and we know this. We work every day and I am happy I am part of a team that work very good together."