Jurgen Klopp's side currently sit in fourth position on 34 points after 18 games, with the Gunners just a point behind them in fifth.
Liverpool ran out 4-0 winners at Anfield in the reverse fixture earlier in the season - can Arsene Wenger's side avoid another humiliation this time round?
|Game||Arsenal vs Liverpool|
|Date||Friday, December 22|
|Time||19:45 GMT / 14:45 ET|
TV CHANNEL & LIVE STREAM
The game will be shown live on television in the United Kingdom (UK) on Sky Sports Premier League and Sky Sports Main Event, and can be streamed on the Sky Go app.
|UK TV channel||Online stream|
|Sky Sports Premier League, Sky Sports Main Event||Sky Go app|
In the United States (US), the Premier League can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
SQUADS & TEAM NEWS
|Goalkeepers||Cech, Ospina, Macey|
|Defenders||Mertesacker, Holding, Mustafi, Koscielny, Chambers, Monreal, Debuchy, Bellerin, Kolasinac, Maitland-Niles|
|Midfielders||Nelson, Wilshere, Willock, Xhaka, Elneny, Ozil|
|Forwards||Iwobi, Sanchez, Welbeck, Lacazette, Giroud, Nketiah, Akpom, Walcott|
Shkodran Mustafi is set to return to first-team action on Friday having sat out Arsenal's midweek Carabao Cup tie against West Ham.
Olivier Giroud sustained a hamstring injury against the Hammers, while Francis Coquelin picked up a knock. Both will miss the game against Liverpool.
Potential starting XI: Cech; Mustafi, Koscielny, Monreal; Bellerin, Xhaka, Wilshere, Kolasinac; Ozil, Sanchez, Lacazette
|Goalkeepers||Mignolet, Karius, Ward|
|Defenders||Lovren, Milner, Gomez, Klavan, Matip, Flangan, Alexander-Arnold, Robertson|
|Midfielders||Wijnaldum, Coutinho, Henderson, Mane, Can, Markovic, Ejaria, Woodburn, Wilson, Brannagan, Oxlade-Chamberlain|
|Forwards||Salah, Solanke, Firmino, Sturridge, Ings, Brewster|
Liverpool are likely to continue with a foward unit of Mohamed Salah, Roberto Firmino, Philippe Coutinho and Sadio Mane on Friday, such has been their success so far this season.
Alex Oxlade-Chamberlain, who started in the 4-0 thrashing of Bournemouth last weekend, is available for selction in what would be his first appearance against his former club.
Potential starting XI: Mignolet; Gomez, Lovren, Klavan, Milner; Henderson, Wijnaldum; Salah, Firmino, Coutinho, Mane
BETTING & MATCH ODDS
Arsenal are considered slight favourites to win at 11/8, with Liverpool 9/5, while a draw comes in at 5/2.
Arsenal have lost their last three Premier League games against Liverpool and will be determined not to let it happen again – they haven’t lost four in a row against them since May 1998.
Klopp's side will come into the game full of confidence having become the first team in top-flight history to have won four consecutive away games by a margin of at least three goals following their 4-0 thumping at Bournemouth last time out.
If the Gunners are to take anything away from the tie then Wenger will need to stifle the Reds' key asset, Salah, who became the first Premier League player to reach 20 goals in all competitions this season in the aforementioned tie against Eddie Howe's Bournemouth.
Arsenal are able to climb above Friday's opponents in the Premier League rankings with a victory, while a draw will see them end the day level on points.
Liverpool have a superior goal difference, however, with their success on the road a major reason as to why - no team has scored more away goals in the Premier League this season.
Gunners shot-stopper Petr Cech comes into the game just one clean sheet away from becoming the first ever goalkeeper to record 200 shutouts in the English top flight, though he’s conceded 14 goals in his five games against Liverpool; at least six more than he has against any other side.