City had a £38 million bid for Bonucci turned down last year but Juve and the 30-year-old are no longer as resistant to offers.
Chelsea have been focused on signing Southampton's Virgil van Dijk, but they may switch attentions to Bonucci if they miss out.
Antonio Conte has outlined the need to boost his squad this summer and he has specifically asked for a centre back, but he could be disappointed with Van Dijk topping the shortlist of several clubs.
Bonucci and Conte have a very good relationship as the Chelsea manager utilised the defender in a back three for most of his games with Juventus and the Italian national team.
Chelsea also are seeking to sign at least one wing-back, and complete deals for a striker and central midfielder before the season starts.
Should Juventus lose Bonucci, the club will target Lazio's Stefan de Vrij.
Andreas Christensen will still return to Chelsea for pre-season, but the centre back will need to prove he is ready in training after two seasons away with Borussia Monchengladbach.