Swansea, quarter-finalists in this competition for the first time in 54 years, are 6/1 (7.0) to secure a historic victory, while Tottenham are 1/2 (1.5) to record their 28th win of the campaign in all competitions.
Spurs' only two FA Cup away games this term – at Newport and Rochdale – have ended in draws and another stalemate is 16/5 (4.2).
Spurs 3/1 to beat Swansea
Harry Kane will be out until at least April with ligament damage, so Heung-Min Son is likely to start up top for Spurs. Toby Alderweireld is out, but Dele Alli should shake off a groin injury he picked up against Bournemouth.
Swansea are without their own top scorer in Jordan Ayew, who is suspended after being sent off in last week’s 0-0 draw at Huddersfield.
His brother Andre is cup-tied along with Andy King, and Leon Britton is likely to miss out with a back issue.
Siding with Swansea
As good a job as Mauricio Pochettino has done at Tottenham, his lack of prioritisation in domestic cup competitions may give hope to the Swans.
In a combined 12 FA and League Cup games under the Argentine’s watch, Spurs have won three and lost seven.
Given that Swansea have lost just two in 16 under Carvalhal in all competitions, the 10/3 (4.33) price on them qualifying - either on Saturday or in a replay - is tempting.
Preview and predictions
For our best bet, we’re taking the 6/4 (2.5) on the Double Chance - Swansea win or draw, a bet that will land should they avoid defeat at the Liberty Stadium.