Despite starting the encounter on a positive note with Hector Bellerin turning the ball into his own net, the Foxes failed to build on the impressive start allowing the Gunners to claw their way back, with Mesut Ozil igniting the comeback with his leveller before Pierre-Emerick Aubameyang's brace sealed the win.
The Nigeria international could have restored the lead to the King Power Stadium outfit in the 58th minute but his powerful header was denied by the crossbar.
And the 21-year-old has expressed his disappointment in the result – their second consecutive league defeat - which has seen them remain in the 11th spot in the log.
"I would say it’s a bit disappointing in the second half, we did our bit in the first half, we did really well," Ndidi told LCFC TV.
"It’s not just about looking at the first half, we need to develop the second half and go from there. It was a tight game. When we conceded the second and then the third, everything just didn’t go our way.
"If we’d have got the penalty and then the ball hadn’t hit the crossbar everything would have worked perfectly for us. We just look forward and take confidence into the next game."
The midfielder who is confident in the 3-5-2 formation deployed by Claude Puel believes that Ozil’s equaliser damaged his side's drive.
"That really crumbled us but I think we did our bit in the first half, if we had stayed 1-0 up going into the second half we would have been more confident.
"Everything is going fine, even though we lost we’re getting used to the formation and doing our bit.
"As I said, we take the first half, also the second half we just need to learn from our mistakes and then correct it towards the next game."