Chelsea have won each of their last five fixtures against Newcastle United at Stamford Bridge, including a 3-1 win when the teams last met at this venue at the beginning of last month.
SportPesa offer 10/27 (1.37) that the Blues cruise into the fifth round with a win against Rafael Benitez's side, while the odds compilers offer 15/4 (3.75) that the match ends all square - as per each of Chelsea's last three home fixtures.
Newcastle have failed to win any of their last 14 FA Cup fixtures away from St James' Park, with the 27/4 (7.75) quote from SportPesa for an away win indicative of the enormity of the task facing the visitors.
Chelsea are expected to rotate heavily ahead of the visit of the Magpies with Pedro likely to feature, whilst Michy Batshuayi is likely to deputise for the injured Alvaro Morata.
Rafa Benitez may be tempted to stick with Ayoze Perez up front after he netted twice in the last round, but loanee Kenedy is ineligible to play against his parent club.
Comfortable for Chelsea?
The Blues have beaten the Magpies by at least two clear goals in each of the last five matches between the teams in west London, so SportPesa's 11/10 (2.10) quote for the Blues (-1) to beat the handicap mark could well prove popular.
The Magpies' miserable away form in the FA Cup has seen them score in just one of their last six ties away from Tyneside, and SportPesa offer 21/20 (2.05) that Benitez's team draw a blank in west London.
Tips and predictions:
Given Newcastle's dreadful away record in this competition, SportPesa's 5/4 (2.25) quote for Chelsea to win without conceding against the shot-shy Magpies could provide punters with a path to profit this weekend.