Bayern Munich midfielder Javi Martinez is set for a spell on the sidelines with an ankle injury.
Martinez has been restored to a defensive-midfield role under Jupp Heynckes this season, having operated chiefly in defence under Pep Guardiola and Carlo Ancelotti, and has made 20 appearances in all competitions.
He has been with Bayern since the summer of 2012.
During his time in Bavaria, the 29-year-old has made 100 Bundesliga appearances and 164 across all competitons.
Martinez will not be adding to that tally any time soon, though, after picking up an untimely knock.
Bayern will have to tinker with their plans as a result, with Heynckes now needing to shuffle his pack.
The game will take place without Javi #Martínez. He sprained his ankle in the final training session and has not travelled to Mainz.— FC Bayern English (@FCBayernEN) February 3, 2018
Bayern head into their meeting with Mainz sat 16 points clear at the top of the Bundesliga table, with another domestic title very much on the cards.