The Premier League champions were halted at Molineux following a 5-1 rout of Huddersfield Town, and Pep Guardiola will be eager to return his side to the top of the table.
Meanwhile, Rafa Benitez's team will be left disappointed by a late 2-1 loss to Chelsea last time out despite equalising towards the end of stoppage time, before Marcos Alonso proved to be the unlikely match-winner for the Blues.
|Game||Manchester City vs Newcastle|
|Date||Saturday, September 1|
|Time||5:30pm BST / 12:30pm EST|
TV Channel, Live Stream & How To Watch
In the United States (US), the game will be shown on NBC Sports and streamed online via the NBC Sports Live app .
|US TV channel||Online stream|
|NBC Sports||NBC Sports Live|
In the United Kingdom (UK), the game can be watched live on BT Sport and streamed on the BT Sport app .
|UK TV channel||Online stream|
|BT Sport||BT Sport app|
Squads & Team News
|Position||Manchester City players|
|Defenders||Stones, Otamendi, Laporte, Walker, Kompany, Mendy, Danilo|
|Midfielders||B. Silva, D. Silva, Fernandinho, Gundogan, Delph, De Bruyne, Foden, Brahim|
|Forwards||Sane, Mahrez, Aguero, Sterling, Jesus|
The big team news for Manchester City is that Leroy Sane has been left out of the squad by Pep Guardiola, and Goal understands it is because the manager is unhappy with the German winger's attitude .
Elsewhere, Gabriel Jesus and Sergio Aguero start in attack, with Riyad Mahrez and Raheem Sterling also starting for the Premier League champions.
Man City XI : Ederson, Walker, Stones, Laporte, Mendy, D.Silva, Fernandinho, Mahrez, Sterling, Jesus, Aguero.
Subs : Muric, Kompany, Gundogan, Delph, Bernardo, Otamendi, Foden.
|Goalkeepers||Dubravka, Darlow, Elliot, Woodman|
|Defenders||Fernandez, Schar, Clark, Lascelles, Yedlin, Dummett, Lejeune, Manquillo, Sterry|
|Midfielders||Ki, Diame, Shelvey, Ritchie, Murphy, Atsu, Aarons, Hayden, Kenedy, Longstaff|
|Forwards||Rondon, Joselu, Perez, Muto|
For Newcastle, Jemal Lascelles returns to the heart of the defence, while Salomon Rondon keeps his place in attack.
Kenedy is back in having been ineligible to face parent club Chelsea, while Ayoze Perez also starts having been named on the bench in the defeat to Maurizio Sarri's men.
Newcastle XI : Dubravka, Yedlin, Clark, Fernandez, Lascelles, Dummett, Diame, Ki, Kenedy, Perez, Rondon.
Subs : Darlow, Sterry, Longstaff, Murphy, Atsu, Muto, Joselu.
Betting & Match Odds
Manchester City are priced at odds of winning 1/10 according to bet 365 , while a draw is available at 8/1. A win for the Magpies is priced at 20/1.
Guardiola's side will rue the fact that some refereeing decisions may have gone against his team in last week's fixture, but will need to regain momentum against Newcastle if they want to continue their hopes of defending their Premier League title.
City and Liverpool are being named as the frontrunners to challenge for the Premier League but the likes of Tottenham and Chelsea – who registered three wins in three – also remain dangerous.
Benitez's side have yet to register a win this season in the Premier League following a summer that was riddled with off-field troubles, losing to Tottenham on opening day and drawing with Cardiff City in their second game.
Newcastle missed a penalty in the final minute in their game against Cardiff and will be eager to register their first win of the new campaign with an unlikely victory over the English champions.
The Magpies will need to recover from a disappointing 3-1 midweek defeat in the Carabao Cup to Nottingham Forest, though the loss would have done little to motivate ahead of the club's toughest challenge in the Premier League against Guardiola's side.