However, the Turin outfit are battling an injury crisis and only have three recognised central midfielders available for the game.
Juve go into the match in superb form and have won 12 of their 13 Serie A matches so far this season, with the only slip-up coming against Genoa in October.
As for SPAL, they are 15th in the table and are just four points ahead of the drop zone.
|Game||Juventus v SPAL|
|Date||Saturday, November 24|
|Time||5pm GMT/ 12pm ET|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live on ESPN+ and streamed on the ESPN app.
|US TV channel||Online stream|
In the United Kingdom (UK), the game can be watched live on TV on Eleven Sports 2, and it can be streamed online via the Eleven Sports app.
|UK TV channel||Online stream|
|Eleven Sports 2||Eleven Sports app|
Squads & Team News
|Goalkeepers||Szczesny, Pinsoglio, Perin|
|Defenders||De Sciglio, Chiellini, Benatia, Alex Sandro, Barzagli, Bonucci, Cancelo, Rugani, Spinazzola|
|Midfielders||Pjanic, Matuidi, Cuadrado, Bentancur|
|Forwards||Ronaldo, Dyabala, Douglas Costa, Mandzukic, Kean|
Juventus XI: Szczesny; Di Sciglio, Bonucci, Rugani, Alex Sandro; Cuadrado, Pjanic, Bentancur, Costa; Ronaldo, Mandzukic.
|Goalkeepers||Gomis, Milinkovic-Savic, Thiam|
|Defenders||Bonifazi, Cionek, Djourou, Felipe, Simic|
|Midfielders||Costa, Dickmann, Everton, Fares, Kurtic, Lazzari, Missiroli, Schiattarella, Valdifiori, Valoti, Vitale|
|Forwards||Antenucci, Floccari, Moncini, Paloschi, Petagna|
SPAL XI: Gomis; Cionek, Felipe, Bonifazi, Fares; Lazzari, Schiattarella, Kurtic, Missiroli; Antenucci, Petagna
Betting & Match Odds
Unsurprisingly, Juventus are massive favourites for this one and are priced at 1/7 with bet365. An unlikely away win is available at huge 18/1, while a draw is 7/1.
With Napoli not playing until Sunday Juventus know that a win against SPAL will ensure they top the table by nine points, for 24 hours at least.
It’s a busy period of the season for Juve, who between now and the winter break face tough Serie A games against the likes of Fiorentina, Inter and Roma, as well as the Turin derby in three weeks time.
Firstly though, they will have to deal with the threat posed by SPAL. Last time out the Ferrara-based club drew 2-2 with Cagliari, putting to end a seven-game losing streak.
SPAL will know this is perhaps their toughest game of the season, but can draw heart from their last result against Juve, when they drew 0-0 with the reigning Italian champions in March.
Juventus will be hoping to do a bit better in front of goal on Saturday, and will no doubt be aided this time by Cristiano Ronaldo.
The Portuguese attacker has registered eight league goals so far this season, with only Genoa’s Krzysztof Piatek scoring more than him in Serie A.