Arsene Wenger's side come into the game having snatched a late victory over Burnley in their last outing, a result which saw them leapfrog Tottenham into fourth, and they will be keen to continue their ascent with a win against the Terriers.
That will, however, depend on the result of Chelsea's game against Swansea, which takes place across London at the same time.
|Game||Arsenal vs Huddersfield Town|
|Date||Wednesday, November 29|
|Time||19:45 GMT / 14:45 ET|
TV CHANNEL & LIVE STREAM
The match will not be available to watch live on television or to live stream in the United Kingdom, but you can follow live updates on Goal.
|UK TV channel||Online stream|
In the United States (US), the match will not be available to watch live on television but it can be watched by live stream online using the NBC Sports Gold service.
|US TV channel||Online stream|
|N/A||NBC Sports Gold|
SQUADS & TEAM NEWS
|Goalkeepers||Cech, Ospina, Iliev, Macey|
|Defenders||Debuchy, Mertesacker, Mustafi, Koscielny, Holding, Monreal, Bellerin, Chambers, Kolasinac, Osei-Tutu|
|Midfielders||Ramsey, Ozil, Xhaka, Iwobi, Elneny, Maitland-Niles, Cazorla, Coquelin, Wilshere, Sheaf, Willock, Dragomir, Gilmour, McGuane, Reine-Adelaide|
|Forwards||Sanchez, Giroud, Walcott, Akpom, Lacazette, Welbeck, Dasilva, Nelson, Nketiah|
Mesut Ozil missed the Gunners' last game due to illness and Wenger says that the Germany international will be monitored, but he is expected to be available.
Alex Iwobi, who replaced Ozil in the line-up against Burnley, sustained a dead leg during the game and is likely to miss out. Santi Cazorla is also unavailable after enduring a further setback in his recovery.
Potential Arsenal starting XI: Cech; Monreal, Koscielny, Mustafi, Bellerin, Kolasinac; Xhaka, Ramsey, Ozil; Sanchez, Lacazette.
|Goalkeepers||Lossi, Coleman, Green, Schofield|
|Defenders||Smith, Malone, Cranie, Lowe, Schindler, Jorgensen, Stankovic, Hadergjonaj, Hefele|
|Midfielders||Whitehead, Hogg, Billing, Mooy, Sabiri, Van La Parra, Williams, Ince, Palmer|
|Forwards||Kachunga, Depoitre, Quaner, Mounie, Lolley|
The chief absentee for Huddersfield is Rajiv van La Parra who begins a three-match suspension after being sent off against Manchester City.
Philip Billing is out, as is Kasey Palmer, but Steve Mounie is available and may come into the team to replace Van La Parra.
Potential Huddersfield starting XI: Lossi; Smith, Jorgensen, Schindler, Malone; Hogg, Mooy, Ince, Williams, Mounie; Depoitre.
BETTING & MATCH ODDS
Arsenal are heavy 1/5 favourites to win according to dabblebet, while Huddersfield are rated at 14/1 to beat the Gunners. A draw between the teams is available at 11/2.
Despite some early-season wobbles, Arsenal have forced their way into the top four ahead of the busy festive period and could find themselves breathing down the neck of Manchester United ahead of their clash this coming weekend.
Wenger's side managed to claim three points away to Burnley at the weekend despite a below-par performance and the players will no doubt be buoyed by the prospect of clawing their way back into the title race.
However, beating Huddersfield will not necessarily be a straightforward task, as league leaders Manchester City found last week and Man United found to their detriment when they lost back in October.
David Wagner's recently promoted team have upped their game against more vaunted opponents this season and the Gunners will have to be on their guard against complacency if they are to secure victory.
A win will push them to within four points of the Red Devils, which will make their upcoming meeting at the Emirates this Saturday all the more interesting.