Having collected a red card in the first leg of the heavyweight European clash, the World Cup winner was restricted to a spectator role at Parc des Princes on Wednesday.
United had it all to do against PSG having suffered a 2-0 defeat at Old Trafford, with many having predicted they would struggle to pull off an unlikely result in the French capital.
They were without Pogba and a number of injured stars, including Nemanja Matic, Alexis Sanchez and Juan Mata.
Ole Gunnar Solskjaer’s remarkable influence over the Red Devils was, however, to deliver another thrilling success.
United opened the scoring inside two minutes through Romelu Lukaku, with the Belgian netting a second on the half-hour mark.
Juan Bernat had briefly restored parity for the hosts, but the visitors were in the mood to claim the most notable of scalps.
They did require assistance from VAR to get over the line, with a controversial stoppage-time penalty awarded after Presnel Kimpembe was deemed to have handled inside the box.
Marcus Rashford crashed home from the spot, sending those of a United persuasion into raptures – including Pogba and former Red Devils defender Evra.
And the celebrations would unlikely have gone down well with the home support, with the 37-year-old having previously riled fans with a reminder of their 6-1 bashing at the hands of Barcelona.
His famous "I love this game" line was brought out as he made everybody around him aware of where his allegiances lie.
Pogba was also happy to get in on the act.
He would have feared the worst as a depleted United side readied themselves for the toughest of continental tests.
Solskjaer has returned fighting spirit and a sense of belief to the Red Devils’ ranks, though, and they had been quick to talk up their chances before a ball was kicked.
They are now through to the Champions League quarter-finals and still on course to claim a remarkable European triumph, with the draw for the last eight to be held on March 15.