The striker, who formed a devastating partnership with Mohamed Salah and Roberto Firmino, only recently signed a new long-term deal on Merseyside, and has played down reports of an exit.
Madrid boss Zinedine Zidane is thought to view the Senegal international as a key prospective asset and now Seck has weighed in on the rumours, feeling that Madrid is a better option for the forward due to its prestige, despite a personal preference for Barcelona.
“Everybody in the world knows that Mane is in the top ten best footballers in the world and he has achieved significant success at Liverpool in the past season,” Seck stated to the Mirror.
“He alongside Mo Salah and Firmino are phenomenal. But this is football and he won the Champions League last season and he has the chance to go to Madrid.
“For me I think it’s the best club in the world. Even if I am a Barcelona fan, I still think Real is the best and Mane should be thinking of that offer seriously.
“The career of a footballer is very short and sometimes you don’t get the chance a lot so if it’s there, and I think Zidane likes him, why not?
With Senegal still competing in the Africa Cup of Nations, where Mane is a stand-out performer, he is not expected to return to Liverpool until they have completed their pre-season commitments in North America.