Tottenham will hope to avoid a potential banana skin this weekend as they aim to continue their Premier League title challenge.
Spurs have emerged as the best of the rest in recent weeks and lie in second, 10 points behind Chelsea, who would appear to be the champions-elect.
However, the Blues have yet to confirm their coronation, and Mauricio Pochettino's men will hope to narrow the gap when they travel to Turf Moor to take on Burnley.
Initially Spurs held serious fears that Kane could miss the remainder of the season but he is now reportedly targeting a return in the North London derby against Arsenal on April 30.
Erik Lamela, meanwhile, may have played his last game for the club after it was confirmed that he will undergo hip surgery, amid rumours suggesting that he could return to Italy this summer.
Danny Rose, too, will be absent from this weekend's encounter as he continues his recovery from an MCL knee ligament injury, while striker Vincent Janssen is a doubt after being struck down with flu.
Spurs have no players suspended for the encounter with Burnley.
POTENTIAL TOTTENHAM LINE-UP
Spurs are set to play in their usual 3-4-3 formation, and Son Heung-Min is almost certain to be trusted to deputise for Kane up front.
With Janssen a doubt, the South Korean has a strong claim to start through the middle, after impressing during the 2-1 win over Southampton prior to the international break.
However, the forward played 90 minutes in midweek as his national team defeated Syria 1-0 in a World Cup qualifier, so Pochettino must be wary of his potential fatigue.
Elsewhere, the side is unlikely to change much from the victory over Southampton, with Janssen the only player to return from international duty carrying an issue.
BURNLEY TEAM NEWS
Sean Dyche's men have been quietly impressive in the Premier League this season and currently sit 13th, eight points above the relegation zone.
A 0-0 draw with Sunderland sent the Clarets into the international break on something of a mediocre note but they have reason to be optimistic ahead of the clash with Spurs, with Michael Keane now a fully-fledged England international after his outing against Germany last week.
In terms of injuries, Burnley could be without Scott Arfield after the Canada international picked up a knock on international duty.
Elsewhere, Johann Gudmundsson will definitely miss out while Dean Marney is a long-term injury absentee.
BEST OPTA MATCH FACTS
Burnley have won just one of their five previous Premier League games against Tottenham (W1 D1 L3), in May 2010 when Brian Laws' already-relegated side won 4-2.
Spurs have scored at least two goals in four of their five previous Premier League matches against the Clarets, but failed to score in their last visit to Turf Moor in April 2015.
Dele Allí has been involved in 10 goals in 10 Premier League appearances for Tottenham in 2017 so far (eight goals, two assists).
TV COVERAGE & KICK-OFF TIME
The game is due to kick off at 15:00 GMT on Saturday, and will not be televised live in the UK. Highlights will be aired on Match of the Day on BBC One at 22:30.