Marcus Rashford's eighth-minute effort from the penalty spot separated the teams to hand the Foxes their first Premier League defeat of the season.
It's a first defeat of the season for the Foxes.#MunLei— Leicester City (@LCFC) September 14, 2019
Ndidi was on parade from start to finish while his compatriot Kelechi Iheanacho and Ghana's Daniel Amartey were missing in action for Brendan Rodgers' side.
Aside from his marshalling display in the middle of the park, the 22-year-old created several chances as the Foxes hunted for an equaliser.
A late-minute effort from the Nigeria midfielder could not cause a problem for David De Gea as it went wide off target.
Ndidi! 😖— Leicester City (@LCFC) September 14, 2019
The Nigerian volleys a left-footed strike just wide of De Gea's net.#MunLei
Leicester City will be aiming to bounce back from the defeat when they host Tottenham Hotspur at the King Power Stadium next Saturday.