The duo were in top form as City defeated Liverpool last time out, with Guardiola making one change in total to the side that thumped Jurgen Klopp's side.
Elsewhere, Ederson has recovered sufficiently from the facial injuries he sustained in the collision with Sadio Mane on the weekend and he keeps his place in goal.
Despite scoring two goals against Liverpool, Leroy Sane has to settle for a place on the bench once again, while Raheem Sterling, banned for the win over the Reds, is also back in the squad.
Man City starting XI: Ederson, Walker, Stones, Otamendi, Mendy, Fernandinho, De Bruyne, Bernardo, Silva, Jesus, Aguero.
Subs: Bravo, Danilo, Sterling, Gundogan, Mangala, Delph, Sane.
Feyenoord starting XI: Jones, St. Juste, Botteghin, van der Heijden, Nelom, Vilhena, El Ahmadi, Boetius, Berghuis, Kramer.
Subs: Bijlow, Diks, Geertruida, Tapia, Toornstra, Larsson, Vente.