Born to Ghanaian parents in Italy, the Trabzonspor striker is enjoying prolific early days in the national shirt having scored twice in two games.
On Tuesday, he was among the scorers as Kwesi Appiah's outfit beat Mauritania 3-1 in an international friendly in Accra, just three days after scoring on his debut to help Ghana beat Kenya 1-0 on the final day of the Afcon qualifiers on Saturday.
“Everybody wants to be in a great tournament such as the Africa Cup of Nations and I would like to be part of the team," Ekuban told the media on Tuesday.
"Of course, missing out will not be nice for me but I will not be upset.
“It will only mean that other players have performed better in the build-up and maybe, next time, I will get the chance.”
Reports also say coach Appiah is still engaging Spain youth and Athletic Bilbao forward Inaki Williams for a switch in international allegiance, a situation which could reduce Ekuban's chances of playing at the June 21 - July 19 tournament in Egypt.
At club level, the 25-year-old, on loan from English side Leeds United, has scored seven goals in 28 matches so far in all competitions for Trabzonspor this season.