Unai Emery recorded his first win as Arsenal manager against West Ham last weekend and will be looking to continue in the same vein when the Gunners travel to Cardiff on Sunday.
Emery's side looked convincing against the Hammers, with Alexandre Lacazette impressing during a second-half cameo appearance.
Arsenal last played Cardiff in the 2013-14 season and are unbeaten against the Welsh side since 1961.
Left-back Sead Kolasinac is out for eight to ten weeks with a knee injury while Ainsley Maitland-Niles has suffered a fracture in his left leg and will be out for six to eight weeks.
Long-term absentee Laurent Koscielny is aiming to return to training in November, as will Carl Jenkinson who has a significant sprain to his right ankle.
Arsenal have no suspensions for this game.
Possible Arsenal starting line-up
Emery could hand Lucas Torreira his first full Premier League start in defensive midfield while Nacho Monreal or Stephan Lichtsteiner will start at left-back.
Mesut Ozil is expected to return to the starting XI while Alexandre Lacazette could start in the forward position following his impressive cameo appearance against West Ham.
Cardiff team news
Cardiff boss Neil Warnock is waiting on the fitness of star winger Junior Hoilett ahead of Sunday's match after the Canadian picked up a groin problem during the stalemate with Huddersfield
Nathaniel Mendez-Laing is out for three months with a posterior cruciate injury while Aaron Gunnarsson is making progress on a knee injury and could be back after the international break.
TV coverage & kick-off time
Kick-off is 1:30pm BST (10am ET) on Sunday September 02, and the game will be shown on Sky Sports in the United Kingdom. It will be shown on NBC in the United States, and on various channels around the world.
Best Opta match facts
Cardiff are winless in their last 13 games against Arsenal in all competitions (D5 L8), since a 3-2 away win in February 1961. o Arsenal won both previous Premier League meetings with Cardiff back in 2013-14, including a 3-0 triumph at the Cardiff City Stadium. o Four of Arsenal’s five Premier League goals against Cardiff have come in the final five minutes of games.
Cardiff are yet to play a single Welshman in the Premier League this season, giving 1,358 minutes to Englishmen, while opponents Arsenal – who are one of six clubs to have used a Welsh player this season (Aaron Ramsey) - have given fewer minutes to English players than any other side (50).
Matteo Guendouzi could become only the fourth teenager to start each of Arsenal’s first four matches of a Premier League season, after Nicolas Anelka (1998-99), Cesc Fabregas (2004-05 and 2006-07) and Johan Djourou (2006-07).
Since scoring from a corner against West Ham in April, each of Arsenal’s last 16 Premier League goals have all come from open play.
Arsenal have faced more shots on target than any other side in the Premier League so far this season (24).