Sundowns will host the one off match at Loftus Versfeld by virtue of being the 2016 Caf Champions League winners.
Mosimane has stressed the importance of such an occasion and believes Masandawana have a duty to represent South Africa and not just the club.
“This game is about history, records and legacy,” Mosimane told the media.
“We can’t ask for more because it is at home. We have to make sure we bring another cup home. It’s not a cup for Sundowns but for the PSL and South Africa, it is not about the club.”
The 52-year-old is looking forward to the game and has been given the all clear with regards to players at his disposal.
“The team is ready we don’t have any major injuries,” Mosimane said.
Mosimane also emphasised the role that home ground advantage will play and will not entertain excuses as The Brazilians will try to win the match.
“We earned this advantage. You only earn this advantage when you win the Champions League. We earned it,” Mosimane added.
“Its home advantage, it’s our pitch so there is no excuse. So we’ll try to win the match.”
The former Bafana Bafana coach, however, is weary of the Mazembe attack and will not take anything for granted.
“I respect Mazembe. I think they have the same or, maybe even better attack than Sundowns. They have quality.
“It’s bragging rights also. It’s not all about history or records and Mazembe still believe they are good. We played them here and beat them but we went to Lubumbashi and they beat us and their score eliminated us.
“They have (Rainford) Kalaba, they still have quality. We can play, let’s play,” Mosimane emphasised.
Mosimane has made it known that he will be relying on his more senior players such as Khama Billiat and Anthony Laffor for the clash against the Ravens but was full of praise for dynamo Percy Tau’s performances of late.
“Percy has been key, I told him just be patient and you’ll win player of the month,” Mosimane said.