The England international replaced Juan Mata after 70 minutes, bringing up his half century in the process, and was immediately involved in the action.
Rashford raced to the byline and got the ball across to set-up Zlatan Ibrahimovic for what was United's second goal of the night as they cruised to a comfortable Europa League last 32 first-leg triumph.
Still only 19 years old, the United academy graduate has reached the 50 appearances milestone in a little under a year.
Having joined the club as a seven-year-old, Rashford has risen up the ranks and made an instant impact as he became United's youngest ever scorer in Europe when he struck twice against Midtjylland on his debut.
In total, the young forward has made eight appearances in the Europa League since his incredible debut, while he's featured in 11 domestic cup matches and 31 Premier League games.