Jose Mourinho's team have now secured a second-place finish in the Premier League following their 0-0 draw with West Ham on Thursday night.
Watford sit mid-table, having won 11 games this season, although their victory over Newcastle last weekend ended a run of seven matches without a win.
In the two clubs' last encounter, the Red Devils won 4-2 at Vicarage Road in late November and they will hoping to repeat that at Old Trafford.
|Game||Manchester United vs Watford|
|Date||Sunday, May 13|
|Time||3:00pm BST / 10:00am ET|
|Stream (US only)||fubo TV (7-day free trial)|
TV Channel & Live Stream
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|NBC Universo / NBCSN||fubo TV (7-day free trial)|
In the United Kingdom (UK), the game can be watched live on TV on Sky Sports Premier League and it can be streamed live online using Sky Go.
|UK TV channel||Online stream|
|Sky Sports Premier League||Sky Go|
Squads & Team News
|Position||Man Utd players|
|Goalkeepers||De Gea, Romero, Pereira|
|Defenders||Blind, Lindelof, Bailly, Jones, Smalling, Rojo, Shaw, Valencia, Darmian|
|Midfielders||Pogba, Mata, Lingard, Carrick, Young, Matic, McTominay, Gomes, Fellaini|
|Forwards||Martial, Rashford, Lukaku, Sanchez|
Romelu Lukaku is still out after injuring his ankle during the Arsenal game a few weeks ago, while Marouane Fellaini remains doubtful due to a muscular injury.
Potential Man Utd XI: Romero; Blind, Bailly, Smalling, Carrick, Pogba, Matic, Mata, Martial, Sanchez; Rashford.
|Goalkeepers||Gomes, Karnezis, Bachmann|
|Defenders||Janmaat, Britos, Kaboul, Prodl, Mariappa, Wague, Cathcart, Zeegelaar, Holebas, Kabasele, Hoban|
|Midfielders||Cleverley, Ndong, Chalobah, Doucoure, Hughes, Carrillo, Capoue, Pereyra|
|Forwards||Deulofeu, Deeney, Richarlison, Sinclair, Gray, Lukebakio, Okaka|
Nathaniel Chalobah could potentially make a return after a knee injury but is not expected to start. A number of other Watford players also remain out injured, including Younes Kaboul, Tom Cleverley and Tommie Hoban.
Potential Watford XI: Gomes; Janmaat, Holebas, Cathcart, Kabasele; Doucoure, Hughes, Capoue, Pereyra; Deeney, Gray.
Betting & Match Odds
Man United are favourites to win at odds of 2/5, according to dabblebet, while visitors Watford are priced at 13/2. A draw is available at 15/4.
Jose Mourinho's team may not have won the league but still have the chance to claim the FA Cup and the Red Devils will hope Sunday's game against Watford will be good preparation for next week's final against Chelsea.
The final Premier League game of the season will be Michael Carrick's last match as a player before joining Mourinho's coaching staff and he will captain the team. Other changes to the starting line-up will include putting Sergio Romero in goal against the Hornets in place of David de Gea, who claimed his first Golden Glove award after keeping his 18th league clean sheet of the season in Thursday's 0-0 draw at West Ham.
“It is normal that Michael Carrick is captain at Old Trafford for the last game of his career," the United manager told reporters after the game at the London Stadium. "David de Gea will be rested, so it gives a chance for Sergio Romero to play. I can make changes."
Watford lost 4-2 at home against United earlier this season, but come into the match on the back of beating Newcastle last week.
They will be hoping to end the season on a high against a United side who, while beating the likes of Manchester City, Tottenham and Arsenal recently, have suffered surprise defeats by West Brom and Brighton.