The 26-year-old forward is a talismanic presence for his country, with his efforts having helped to fire them to the 2018 World Cup finals in Russia.
He has a key role to play for the Pharaohs in the future, but is set to be awarded a much-needed break.
That news will have been welcomed at Anfield, with Liverpool desperate to keep key men fresh as they endeavour to secure a first top-flight crown in 29 years.
Instead, he will now be allowed to remain in England and rest.
Vice-president of the Egyptian Football Association, Ahmed Shobier, said to KingFut: “Mohamed Salah will not play the Niger game in the AFCON qualifiers or the Nigeria friendly.
“Ahmed Hegazi will probably also be left out of the squad.”
Hegazi is currently on the books at West Brom, so they will also be delighted to discover that no international risks will be taken over the coming weeks.
The Baggies are pushing for promotion out of the Championship, with Darren Moore hoping to deliver a return to the Premier League at the first time of asking.
With Javier Aguirre set to overlook Hegazi, he will be given the chance to ready himself for the domestic challenges to come.
The same will be true for Salah.
Liverpool have seen a man who netted 44 goals across all competitions last season record another 19 in the current campaign.