The annual Super Cup will now be staged at Afraha Stadium in Nakuru and not Kasarani.
The Cup defending champions Gor Mahia have been drawn to face Zanzibar side Jeshi la Kujenga Uchumi in the battle of the 'Armies'.
Tanzanian giants Simba SC will square it out against another Kenyan Premier League side Kariobangi Sharks. Just like Homeboyz, Sharks are also making their first appearance in the competition that has been expanded to eight teams.
The 2017 losing finalist AFC Leopards will clash with Singinda United on day two of the knock out tournament with winners proceeding to the semi-finals set for June 7.
Full fixtures: June 3: Kakamega Homeboyz v Yanga SC and Gor Mahia v JKU.
June 4: Kariobangi Sharks v Simba SC.
June 5: AFC Leopards v Singida United.