The Blues are currently leading the way in Group L after winning all four of their matches to date and they have already booked their place in the knockout stage.
Maurizio Sarri is eager for his side to go into the draw for the last 32 as group winners and wants to see an improvement on their last outing, in which they lost 3-1 against Tottenham .
The teams played out a close encounter when they met in Greece back in September, with the Blues coming out on top with a 1-0 win .
|Game||Chelsea vs PAOK|
|Date||Thursday, November 29|
|Time||8pm GMT / 3pm ET|
|Stream (US only)||fuboTV (7-day free trial)|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|Galavision||fuboTV (7-day free trial)|
In the United Kingdom (UK), the game can be watched live on TV on BT Sport 2 and it can be streamed live online using the BT Sport app.
|UK TV channel||Online stream|
|BT Sport 2||BT Sport app|
Squads & Team News
|Goalkeepers||Kepa, Caballero, Bulka|
|Defenders||Rudiger, Alonso, Zappacosta, Cahill, Christensen, Azpilicueta, Luiz, Emerson|
|Midfielders||Fabregas, Jorginho, Kante, Barkley, Pedro, Loftus-Cheek, Kovacic, Hudson-Odoi, Willian,|
Eden Hazard will miss the game as a precaution due to an ankle complaint, but should be available for the weekend's game against Fulham. Victor Moses is another injury concern and will be unavailable, as will Ethan Ampadu.
Callum Hudson-Odoi makes a rare start under Maurizio Sarri as one of 10 changes from the defeat to Tottenham.
Chelsea XI: Kepa; Zappacosta, Christensen, Cahill, Emerson; Barkley, Fabregas, Loftus-Cheek; Pedro, Giroud, Hudson-Odoi.
|Goalkeepers||Rey, Paschalakis, Siampanis|
|Defenders||Matos, Varela, Tosca, Malezas, Crespo, Vieirinha, Lyratzis, Khacheridi, Kitsiou|
|Midfielders||El Kaddouri, Mauricio, Pelkas, Limnios, Wernbloom, Biseswar, Chakhov, Warda, Canas|
|Forwards||Prijovic, Carelas, Akpom, Jaba|
PAOK have not reported any fresh injury concerns and are free of suspensions, so should have a full squad to choose from.
PAOK XI: Paschalakis; Matos, Crespo, Khacheridi, Vieirinha; Wernbloom, Mauricio; Jaba, Shakhov, El Kaddouri; Prijovic.
Betting & Match Odds
Chelsea are strong favourites to win at Stamford Bridge according to bet365 , who price the Blues at 1/3. PAOK are 10/1 to win and a draw is available at 9/2.
With their place in the next round already confirmed, Chelsea have the opportunity to rotate their squad somewhat and Sarri is set make a number of changes.
The Italian coach was left incensed by the nature of his side's capitulation against Spurs at the weekend and is demanding a serious improvement ahead of a busy December.
"It is an important match because we want to see a reaction," Sarri told reporters. "But I also want to see a reaction in the next Premier League match and see that we have learnt our lesson.
"I think I will make big changes to the side because in December we have to play 10 matches so now we need to change, regardless of the last result."
The defeat against Spurs was the Blues' first of the season and fans will be hoping that it was just a blip, rather than the early sign of decline.