The English champions currently occupy second place in Group F with French side Lyon placing first, and will need to register victory against the Ukrainian side if they want to boost their chances of progressing to the last 16 phase.
Pep Guardiola's side lost to Lyon in their opening group stage game but bounced back with a dramatic win over last-placed Hoffenheim in their most recent European outing.
|Game||Shakhtar Donetsk vs Man City|
|Date||Tuesday, October 23|
|Time||8pm BST / 3pm EST|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial) .
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|Univision En Vivo||fubo TV (7-day free trial)|
In the United Kingdom (UK), the game can be watched live on BT Sport 3 and streamed via BT Sport Live.
|UK TV channel||Online stream|
|BT Sport 3||BT Sport Live|
Squads & Team News
|Position||Shakhtar Donetsk players|
|Goalkeepers||Shevchenko, Pyatov, Kudryk|
|Defenders||Butko, Kryvtsov, Khocholava, Ordets, Matviyenko, Ismaily, Rakitskiy|
|Midfielders||Stepanenko, Taison, Bentinho, Marlos, Patrick, Nem, de Andrade Barberan, Robson, Totovytskiy, Bolbat, Kovalenko, Danchenko, Dos Santos Pedro|
Taison is still recovering from a knee injury sustained in the 1-1 draw against Zorya Luhansk on October 7 and will not feature in the match against Man City.
Shakhtar Donetsk XI: Pyatov, Matviyenko, Kryvtsov, Rakitskiy, Ismaily, Fernando, Stepanenko, Maycon, Wellington Nem, Kovalenko, Junior Moraes
|Position||Man City players|
|Goalkeepers||Ederson, Grimshaw, Muric|
|Defenders||Walker, Kompany, Stones, Laporte, Mendy, Otamendi|
|Midfielders||De Bruyne, B. Silva, D. Silva, Fernandinho, Mahrez, Zinchenko, Foden, Diaz|
|Forwards||Jesus, Sterling, Sane, Aguero|
Kevin De Bruyne will make his first start for City since August after making his return from a knee injury off the bench on Saturday against Burnley.
Kyle Walker only makes the bench after returning from international duty with England having picked up a groin injury, while Danilo has not travelled with the squad following an ankle injury sustained during Brazil duty.
Fabian Delph and Ilkay Gundogan have also been left out of the squad, and second-choice Claudio Bravo remains sidelined with a long-term injury.
Man City XI: Ederson; Laporte, Otamendi, Stones, Mendy; Fernandinho, De Bruyne, Silva; Mahrez, Sterling, Jesus
Betting & Match Odds
Man City are priced at odds of winning 4/11 according to bet 365 , while a draw is available at 5/1. A win for the Shakhtar is priced at 7/1.
Guardiola's side will be shifting their focus to the Champions League this weekend after their 5-0 win over Burnley solidified their status as Premier League table-toppers, level on points with Liverpool but ahead on goal difference.
Manchester City are currently second Group F and will want to win against Shakhtar Donetsk to secure a top-two spot, falling behind to Hoffenheim in their last Champions League fixture 1-0 but the likes of Sergio Aguero and David Silva both netting to claim the victory.
The Ukrainian side have drawn both of their Champions League ties so far and will be buoyed by the form of new arrival Junior Moraes, who has netted 12 goals in 15 matches so far this campaign.
Shakhtar Donetsk will have a strong chance of progressing to the knockout phase of the tournament, however, should they manage to defeat Manchester City at home on Tuesday.
The two sides previously met in last year's Champions League with both sides winning their home fixture in the group stage.
Shakhtar are unbeaten in eight meetings with English opponents at home, while City have registered victory just once in three attempts in Ukraine – losing last season's away fixture 2-1.