The annual showcase sees the North American league's standout performers take to the pitch on the same team and face a high-profile European club, with Arsenal last year's guests.
Madrid are the participants for 2017 and they will come up against some familiar faces in Kaka, Bastian Schweinsteiger and David Villa.
|Game||MLS All-Stars vs Real Madrid|
|Date||Wednesday, August 2|
|Time||20:00 (local) / 21:00 ET|
TV CHANNEL & LIVE STREAM
In the UK, the match will be available to watch live on television at 02:00 on Thursday morning on Sky Sports Football and by stream via Sky Go.
|UK TV channel||Online stream|
|Sky Sports Football||Sky Go|
In the US, the match will be available to watch live on television on FS1 and in Spanish on Univision. It can also be streamed on Fox Sports Go.
|US TV channel||Online stream|
|FS1 / Univision (Spanish)||Fox Sports Go|
SQUADS & TEAM NEWS
|Position||MLS All-Stars players|
|Defenders||Beasley, Garza, Grana, Hedges, Kappelhof, Parkhurst, Van Damme, Zusi|
|Midfielders||Acosta, Almiron, Bradley, Dos Santos, Kaka, McCarty, Piatti, Schweinsteiger, Valeri|
|Forwards||Altidore, Dwyer, Giovinco, Nikolic, Villa|
The first 11 players in the MLS team were selected by fan votes. Ten were picked directly by supporters, while the 11th - Sebastian Giovinco - made it in as the player who scored the most goals in FIFA 17 games during the voting period.
The rest of the squad was picked by Chicago Fire and All-Star Game coach Veljko Paunovic as well as league commissioner Don Garber, who gets two selections.
Potential starting XI: Howard; Zusi, Hedges, Van Damme, Beasley; Almiron, Schweinsteiger, Bradley, Kaka; Nikolic, Giovinco.
|Position||Real Madrid players|
|Goalkeepers||Navas, Casilla, Yanez, L. Zidane|
|Defenders||Carvajal, Ramos, Varane, Nacho, Marcelo, Theo, Quezada, Tejero, Achraf, Manu|
|Midfielders||Kroos, Casemiro, Modric, Isco, Ceballos, Kovacic, Oscar, Franchu|
|Forwards||Benzema, Bale, Vazquez, Gomez, Mayoral|
Cristiano Ronaldo will not feature in this match after being given an extended break to recover from his exertions at the International Champions Cup.
Potential starting XI: Navas; Carvajal, Varane, Nacho, Marcelo; Modric, Casemiro, Kroos; Bale, Benzema, Isco.
BETTING & MATCH ODDS
Real Madrid are 7/10 favourites to win, according to Oddschecker, with the All-Stars priced at 23/5 the draw available at 139/50.
YOUR GUIDE TO THE ALL-STAR GAME
New to the MLS All-Star Game? Here's what you need to know...
What is the MLS All-Star Game?
The MLS All-Star Game is an annual match that sees the best players in MLS form a single team to take on a high-profile opponent, which this year is Real Madrid.
In the other four major North American leagues, the All-Star Game is contested exclusively by players from within the league. Those leagues are all split into two divisions (such as the NBA's Eastern and Western Conference), and the top players from each division play each other in a one-off exhibition match once a year.
MLS do it differently, though, by inviting a big-name foreign team to take on their stars.
Who is in the MLS All-Star team?
David Villa, Bastian Schweinsteiger, Kaka and Sebastian Giovinco will all be recognisable names to European fans.
The first 11 players were picked through a fan vote, with supporters directly selecting 10 players and electing an 11th - Giovinco - by playing FIFA 17. The MLS player who scored the most goals on the game during the voting period completed the 'Fan XI'.
From there, All-Star Game coach Veljko Paunovic - who manages the Chicago Fire - selected the rest of the squad with the exception of the two picks made by MLS commissioner Don Garber (Dom Dwyer and Kellyn Acosta).
Where will the All-Star Game be played?
This year's All-Star Game will be played in Chicago. They have their own MLS team - the Chicago Fire, who play at Toyota Park - but the game will be played at Soldier Field, the home stadium of the NFL's Chicago Bears, to accommodate the demand for tickets.
Who are the best MLS players?
Of the big names, Villa and Giovinco remain two of the league's top players and Schweinsteiger has had an immediate impact in Chicago, helping to transform them from MLS's worst team in 2016 to one of its best this year.
Beyond them, watch out for Atlanta United playmaker Miguel Almiron and Chicago striker Nemanja Nikolic, both of whom are having sensational first seasons in North America.