Jesse Were and Lazarous Kambole led Zesco United to a 3-0 demolition of Sonidep on Tuesday as they fired the Zambian outfit into the next round where they will now meet DR Congo giants TP Mazembe.
Kenyan striker Were struck a brace while Kambole weighed in with a goal as Zesco recorded a 5-1 aggregate scoreline win.
For Kambole it was a continuation of his fine form from last season and the first leg where he was again on target in Niger.
Zesco were undoubtedly convincing especially winning away in the first leg, but their next task against five-time African champions Mazembe might not be one that they relish.
Having slowly become regular Caf Champions League group stage campaigners in recent years, including reaching the semifinals two years ago, Zesco now face their toughest test.
Elsewhere, Cotonsport needed a penalty shootout to navigate their way into the first round past Asfb of Burkina Faso.
The Cameroonian giants were stunned in the first leg when they lost 3-1 away, and were almost stunned yet again when Asfb grabbed an away goal through Sani Hien, making it 3-1 in Garoua.
But with score 4-4 on aggregate, the clash headed for dreaded lottery of penalties, and Cotonsport emerged victorious winning 5-3.
Daouda Kamilou had grabbed a brace for Cotonsport while Maximelien Elimbi also found the back of the net for the Cameroonians.
Also, in Lesotho, last season’s group stage contestants Township Rollers were bundled out of the competition by Bantu in Maseru following a penalty shootout.
Having drawn 1-1 in the first leg, the two sides again held each other 1-1 in the return leg with Bantu winning emerging as 4-2 winners after the penalty shootout.
Lesotho international midfielder Hlompho Kalake scored for Bantu while Lemponye Tshireketsho equalised for Rollers before the penalty lottery.
On a day where last season's group stage participants were falling by the wayside, Mbabane Swallows followed suit as they were booted out by Tanzanian giants Simba SC.
Rampant Simba were away but still managed to win 4-0 with Zambian striker Clatous Chama hitting in a brace, while Emmanuel Okwi and Meddie Kagere also scored to complete an 8-1 aggregate win.
Chama and Kagere proved to be on fire after also scoring in the 4-1 first leg win at home.
APR might have been seeing themselves closing in on a place in the next round following a 0-0 first leg result in Kigali. But Club Africain turned on the heat through goals by Bilel Khefifi, Ghanaian striker Derrick Sasraku and an own goal by APR’s Emmanuel Imanishimwe.
Muhadjiri Hakizimana scored for APR but it was not enough for them to proceed to the first round.