The matches against the Central American minnows and Czech Republic in Prague next week are the final games before Tite chooses his squad for the summer finals.
Julio Dely Valdes is back for his third spell in charge of Panama and has overhauled the squad for the showpiece match at Estadio do Dragao.
|Game||Brazil vs Panama|
|Date||Saturday, March 23|
|Time||5pm GMT / 1pm ET|
|Stream (US only)||fuboTV (7-day free trial)|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
In the United Kingdom (UK), the game will not be broadcast live.
|UK TV channel||Online stream|
Squads & Team News
|Goalkeepers||Alisson, Ederson, Weverton|
|Defenders||Fagner, Danilo, Alex Telles, Alex Sandro, Eder Militao, Marquinhos, Miranda, Thiago Silva|
|Midfielders||Allan, Arthur, Casemiro, Fabinho, Felipe Anderson, Lucas Paqueta, Coutinho|
|Forwards||Everton, Firmino, Jesus, Richarlison, Neres|
Tite was expected to recall a number of first-team regulars, including Liverpool goalkeeper Alisson and defender Thiago Silva but elected to go with Ederson and Eder Militao. Dani Alves' absence has Fagner picked over Danilo on the right, with Alex Telles on the other side.
Ajax's David Neres may be in line for his senior debut, though he begins on the bench behind Philippe Coutinho. Richarlison comes in to fill the void left behind by Neymar's injury while Roberto Firmino has been picked over Jesus to lead the attack.
Confirmed Brazil starting XI: Ederson; Fagner, Eder Militao, Miranda, Alex Telles; Lucas Paqueta, Casemiro, Arthur; Richarlison, Firmino, Coutinho.
|Defenders||Murillo, Blackman, Machado, Cummings, Vargas, Escobar, Davis|
|Midfielders||Quintero, Walker, Browne, Godoy, Cooper, Rodriguez|
|Forwards||Stephens, Torres, Fajardo|
Valdes boldly announced his starting XI 24 hours before kick-off and has confirmed a raft of changes for his first match at the helm.
There are 10 alterations in all from the 3-0 defeat to USMNT in January, with captain Fidel Escobar the only survivor from Gary Stempel's final game in charge.
Confirmed Panama starting XI: Mejia; Murillo, Escobar, Cummings, Machado, Davis; Quintero, Godoy, Cooper, Rodriguez; Torres
Betting & Match Odds
Brazil are favourites to win at 1/11 with bet365 . Panama are rated 22/1 to stage an unlikely upset and a draw is priced 17/2.
Six successive wins without conceding a goal have naturally raised expectations as the Selecao prepare to host this summer's Copa America.
Though Panama are not expected to pose a genuine threat, it will represent a chance for Tite to formulate his plans and finalise his squad.
Injuries have denied him the chance to give Dani Alves his international return and a first cap to Real Madrid's Vinicius Jr. Neymar also misses out, though his role this summer is rather more secure.
A seventh win in a row might seem like a formality, but Tite, 57, expects Panama to put up a fight.
"In theory, we are favourites," he explained. "When you go to the field you find difficulties.
"Against Belgium [at the World Cup], it was more than 30 minutes of play, and the first goal chance was Panama.
"Re-structure, reinvent, evolve, adapt to a different reality. The process for the World Cup was atypical. These findings are more challenging. We have to reinvent that reality."
What may assist Brazil is the upheaval which Panama are currently going through.
Valdes has made multiple changes, keeping just nine of the squad which went to the World Cup, in an effort to improve on a dismal run of recent form.
Los Canaleros have lost nine of their last 10 games - scoring just five times in that run - and prevailed once since October 2017. They might be cannon-fodder in this particular encounter but any hints of improvement will be welcomed.