Ndidi went under the knife in September and he has missed over two months of action after he picked up an injury around his abductor against Burnley at the King Power Stadium.
The Nigeria midfield dynamo is expected to return to the Foxes' set-up with Caglar Soyuncu and Ricardo Pereira, who have also recovered from their respective injuries.
“It's an opportunity for us to play some of our players that are coming back from injury and some of our young players,” Rodgers said in his pre-match conference.
“We’ve left a few of our senior players behind, who have all played a lot of football for us and their countries. They can prepare for the weekend.
"Wilfred Ndidi, it’ll be fantastic to see him back. Çaglar Soyuncu will play. Ricardo Pereira as well. Timothy Castagne is still out, we’ll see how he is when we get back."
Some positive news on 3⃣ senior Foxes...— Leicester City (@LCFC) December 2, 2020
"Wilfred Ndidi, it’ll be fantastic to see him back. Çağlar Söyüncü will play. Ricardo Pereira as well. Timothy Castagne is still out, we’ll see how he is when we get back."#UEL #ZrlLei pic.twitter.com/uLK3jkCqui
Ndidi has played just two matches for Leicester City this season. Meanwhile, Ghana’s Daniel Amartey is still on the sidelines as he continues recovery from a hamstring injury he suffered against West Ham United on October 4.
Leicester City are Group G leaders with 10 points after four games and they are a point away from securing their spot in the knockout stage.