The Reds go into the weekend two points adrift of the leaders, who face a tricky away match at Chelsea later in the day.
Having won both Premier League matches between the side last season by an aggregate 7-0 scoreline, they are 5/7 (1.71) favourites with SportPesa to move into top spot by coming out on top here.
Meanwhile, Eddie Howe's men ended a run of four consecutive defeats with a 2-1 win over Huddersfield on Tuesday, and can be backed at 7/2 (4.50) to pull off a shock win in this one.
Just one of the nine previous meetings between this pair has resulted in a draw, but there are odds of 3/1 (4.00) available on them cancelling each other out on this occasion.
Dan Gosling will face a late fitness test after receiving a scan on the knee injury he picked up in the warm-up against Manchester City last weekend, while Adam Smith is out until the new year.
Sadio Mane and Andy Robertson will face late fitness tests after missing the Burnley game due to minor injuries, while Joe Gomez is unlikely to feature after coming off injured at Turf Moor.
Despite their excellent defensive form this season, Jurgen Klopp’s side has actually kept just two clean sheets in the last eight matches on the road.
This record is bound to be tested against a forward line that has failed to score in just one of the previous 11 fixtures, although the fact the Cherries have conceded in six consecutive fixtures suggests goalmouth action is unlikely to be in short supply.
Indeed, odds of 20/21 (1.95) look like excellent value on both teams getting on target in a match featuring over 2.5 goals for Bournemouth’s seventh game in a row, as well as Liverpool’s third in succession on the road.