Otoho on form, but Champions League away record a worry
Otoho are currently on a four-game winning streak in all competitions but they have won none of their previous three away games in the competition.
Their best result was a goalless draw with Zimbabwe's FC Platinum, and Sundowns coach Pitso Mosimane will undoubtedly look to take advantage of this.
Sundowns relish home ground advantage
While Sundowns may have struggled in recent games since their defeat to Otoho, they will favour their chances of overturning the 2-1 deficit at home.
The Brazilians have not lost any of their last six home games in all competitions.
All eyes will be on Thapelo Morena who opened his Champions League account in the first leg. The Downs full-back has relished the opportunity of playing in a more advanced role this season.
Meanwhile, for Otoho, Alex Nganou is one of the men to watch having also found the target alongside Fousseni Yacoubou in the first leg.
Sundowns leak goals
With Sundowns defender Ricardo Nascimento ruled out with injury, the Tshwane giants have not had the same solidity.
Sundowns have conceded four goals in five games across all competitions and this would give Otoho hope to come up with an upset.
Otoho's attacking prowess
Last season, Otoho won the league title by a whopping 10 points.
What made their win all the more impressive was the number of goals they scored in their campaign, 55 in just 26 games.
This could see Sundowns No.1 Denis Onyango, who has only kept one clean sheet so far this season, in for a difficult evening