However, he met with strong resistance from Patrick Vieira’s men as he failed to find the net despite boasting four shots at Jean-Pierre Rivere.
Kasper Dolberg put Nice in front after 13 minutes thanks to Arnaud Lusamba’s assist, but Luiz Araujo levelled matters 11 minutes later.
With no further goals in the game, both teams took one point apiece with Lille still chasing their first French top-flight win of the season.
Before his substitution for Loic Remy in the 88th minute, Osimhen made 29 touches, won two aerial battles with an impressive 88.9% passing accuracy.
Defensively, he got one tackle, one interception, three clearances and nine total passes.
Algeria’s Youcef Atal could not get his second goal of the season before he was replaced by Myziane Maolida with just three minutes left to play.