Following a Fifa ban on Sierra Leone last week, Ghana's matchday three home game against the Leone Stars was called off, giving Kenya and Ethiopia a chance to open up the gap at the top, as all the teams in the group were tied on three points.
However, Ethiopia and Kenya drew goalless in Addis Ababa on Wednesday, and are now each one point above Kwesi Appiah's men with two matches remaining.
"The situation now is a little serious but it is not over for Ghana. With the quality of the Black Stars, I expect Kwesi Appiah to qualify the country to the 2019 Afcon," Polo told Goal.
"It is possible Ghana would've opened a two-point gap in the group if the game against Sierra Leone wasn't cancelled but they still have to deal with the setbacks because they remain the favourites.
"Now that Ethiopia and Kenya have shared the spoils in the other game, all that Ghana need is to win the away fixture against Ethiopia next month and then do everything possible to defeat Kenya at home in the last game. I expect nothing apart from the six points and It is highly possible because we have a good team," he added.
Ghana, who are in search of their first title since 1982, have qualified to the last seven editions of the Afcon, reaching the final on two occasions.