The Balkan nation went down 2-0 against La Canarinha at Anfield but were impressive in the first half and will be looking to build on that showing in their final game before Russia.
Senegal, though, have been extremely underwhelming in 2018 with their three matches seeing them draw against Uzbekistan, Bosnia and Luxembourg.
Playing on home soil Croatia are understandably clear favourites, with bet365 offering them at 3/4 (1.75) for the win.
Sadio Mane sat out the 0-0 draw against Luxembourg last week but should return to boost the Senegalese attack.
While Croatia looked impressive against Brazil, they failed to take the chances they created and Zlatko Dalic's side have now scored just one goal in their last four matches.
Senegal, for their part, have had back to back goalless draws and while the return of Mane will boost them up front, their scoring record in friendlies is far from prolific.
The west Africans have also netted just once in their last four friendlies, which makes opposing goals in Thursday's game the logical selection.
Tips and predictions
Under 2.5 goals is offered at 3/5 (1.60) but more appealing is opposing a high-scoring first half.
nder 0.5 goals in the opening 45 minutes is priced at a healthy looking 6/4 (2.50), with this bet paying out in three of Croatia's last four matches as well as in three of Senegal's last four friendlies.
Prices correct at time of writing. Please gamble responsibly.