Die Mannschaft were crowned as champions of the world in Brazil four years ago and Joachim Low's side are widely tipped to mount a strong defence of their title.
Somewhat surprisingly, though, Germany are without a win in their last four fixtures and Low will be determined to see his side return to winning ways before travelling to Russia.
The world champions are chalked up as 1/2 (1.50) favourites with SportPesa to taste victory this weekend.
Former German international Franco Foda has a 100% record since replacing Marcel Koller as Austria boss, having recorded wins against Uruguay, Slovenia, Luxembourg and Russia respectively.
Bayern Munich 'keeper Manuel Neuer will play his first competitive match since breaking a foot in September as he bids to prove his fitness, while midfielder Toni Kroos looks certain to be rested after playing in the Champions League final for Real Madrid last weekend. Marco Reus is poised to make his first appearance for Die Mannschaft since March 2016.
Austria face Brazil next Sunday, but Foda is expected to name an experienced side for Saturday's showdown against his fellow countrymen, with Neuer's club team-mate, David Alaba, and captain Julian Baumgartlinger of Bayer Leverkusen amongst those likely to line up for the hosts.
Defensive discipline key for the hosts?
Austria have conceded more than one goal in just one of their last 13 matches and SportPesa go 19/4 (5.75) that Foda's side keep a clean sheet against the world champions, while the same firm go 27/4 (7.75) that the hosts win to nil.
Tips and predictions:
Any suggestion of a crisis in the German camp is wildly wide of the mark; before being beaten by Brazil in March Low's side had gone 22 matches without defeat.
With the World Cup just around the corner, Germany will be confident of a convincing performance against Foda's charges and the 27/20 (2.35) quote on offer from SportPesa for the world champions (-1) to beat the handicap mark could prove profitable for punters.