Tied with Manchester United in the second half of Wednesday's Champions League match, Ronaldo scored a stunning volley to give Juve a 1-0 lead in Turin.
The forward was played in by Leonardo Bonucci, and Ronaldo struck the ball first time out of the air, leaving David de Gea with no chance as Juventus surged in front following a tepid first half.
It wouldn't be enough for the hosts to secure victory, though, as Juventus were eventually pegged back on a goal from Juan Mata in the 86th minute that leveled the score, before an own goal from Alex Sandro in the 90th minute gave Manchester United an unlikely 2-1 away win.
Cristiano Ronaldo scores first Champions League goal for Juventus! ⚫️⚪️
And what a way to do it! 😳🙌
UNREAL! 👏 pic.twitter.com/6G9siDmXZp
— Football on BT Sport (@btsportfootball) November 7, 2018
— Bleacher Report Live (@brlive) November 7, 2018Real Madrid star, who hadn't scored on any of his last 20 Champions League shots over a span of 453 total minutes.
*goes to the gym once* pic.twitter.com/GTAQE5yqcY
— Bleacher Report Live (@brlive) November 7, 2018
That Ronaldo wonder-goal already a contender to be runner-up for next year’s Puskas Award behind Salah’s tap-in versus Huddersfield #JUVMNU
— Carlo Garganese (@carlogarganese) November 7, 2018
— United Xtra (@utdxtra) November 7, 2018
— Football Daily (@footballdaily) November 7, 2018
Ronaldo also boosted what was previously a poor goalscoring record against countryman Jose Mourinho, as Wednesday's goal was just his second in 15 appearances against his former manager.
The goal was Ronaldo's eighth in 14 matches with Juventus, while the forward has also contributed six assists to start his career with the Serie A club.
With the loss on Wednesday, Juventus sit on nine points through four matches while the win pushes Manchester United to second in the group with seven points.
Valencia sit third with five heading into the next round of fixtures, where the Spanish club will face the Italian champions while Man Utd take on last-place Young Boys.