Zinedine Zidane's side secured a first-leg victory against the Segunda B outfit, with penalties from Marco Asensio and Lucas Vazquez as almost all of the first-team regulars were rested.
However, it should still go ahead and here, Goal takes a look at everything you need to know about the clash at Montilivi...
REAL MADRID INJURIES
Keylor Navas is doubtful with a groin problem and is expected to be kept in reserve for the game at Wembley on Wednesday, while Mateo Kovacic is also still sidelined.
Dani Carvajal will not feature as he continues to recover from a heart problem.
REAL MADRID SUSPENSIONS
Real Madrid have had a few suspensions already this season, with Cristiano Ronaldo, Marcelo and Sergio Ramos all missing matches in La Liga, but Zinedine Zidane has no players banned for the trip to Girona.
REAL MADRID POTENTIAL STARTING LINE-UP
With Navas set to miss out again, Kiko Casilla will continue in goal for Real Madrid in Girona.
In defence, young right-back Achraf Hakimi looks likely to start again in the absence of Carvajal, while coach Zidane must decide between Nacho or Raphael Varane alongside captain Sergio Ramos.
Further forward, Ronaldo should partner Karim Benzema in attack, with Isco just behind those two in a playmaker role.
GIRONA TEAM NEWS
Girona lost 2-0 at home to Levante in the Copa del Rey on Thursday night, but priority for the Catalan club this season will be to secure survival in La Liga.
The promoted side are currently in 15th place in the Primera Division, with nine points from their nine games after two wins, three draws and four defeats so far.
The Catalans' last home game in La Liga was a 2-1 loss to Villarreal, but Pablo Machin's men did beat Deportivo La Coruna away by the same scoreline last weekend.
Jose Raymundo Luis Suarez is sidelined, while Pedro Alcala is doubtful.
BEST OPTA MATCH FACTS
Sunday's game will be the first competitive fixture between these two teams in all competitions.
Real Madrid have registered 13 consecutive La Liga away wins, the longest streak in the competition's history.
Cristiano Ronaldo will face Girona for the first time in his career. The Portuguese has scored against 31 of the 32 teams he has faced in La Liga (failing to net against Leganes).
Karim Benzema has scored against the 31 teams he has faced in the league (123 goals). He’ll also face Girona for the first time.
TV COVERAGE & KICK-OFF TIME
Girona versus Real Madrid kicks off at 16:15 local time at Montilivi on Sunday and will be broadcast live from 15:10 UK time on Sky Sports Football.