Braces from Miguel Almiron and Kevin Kratz saw Atlanta to a 4-1 win over the Montreal Impact.
Montreal took a surprise lead in the 13th minute, Saphir Taider heading in the opener.
The Impact held onto that advantage until the final 20 minutes, when Atlanta struck four times.
Almiron netted a penalty after a handball in the area before Kratz curled in a wonderful 25-yard free kick.
After Almiron completed his brace, Kratz produced from another free kick to seal Atlanta's win and move the club two points clear atop the Eastern Conference.
Zlatan Ibrahimovic's LA Galaxy conceded a late penalty to go down 3-2 to the Red Bulls at StubHub Center.
New York took a 2-0 lead thanks to Daniel Royer and Florian Valot, who were both set up for simple finishes by Bradley Wright-Phillips.
Ibrahimovic's fine pass set up Ola Kamara to bring Galaxy back into the game and Giovani dos Santos equalised with a close-range finish.
But the Red Bulls scored an 84th-minute winner, Kaku tucking away a late penalty.